{"id":16062,"date":"2012-08-16T22:05:15","date_gmt":"2012-08-16T22:05:15","guid":{"rendered":"https:\/\/www.canaaf.org\/traitement-de-lalopecie-areata-par-les-antihistaminiques\/"},"modified":"2012-08-16T22:05:15","modified_gmt":"2012-08-16T22:05:15","slug":"traitement-de-lalopecie-areata-par-les-antihistaminiques","status":"publish","type":"post","link":"https:\/\/www.canaaf.org\/fr\/traitement-de-lalopecie-areata-par-les-antihistaminiques\/","title":{"rendered":"Traitement de l\u2019alop\u00e9cie areata par les antihistaminiques"},"content":{"rendered":"

Publi\u00e9<\/strong>: ao\u00fbt, 2012<\/p>\n

Traitement de l\u2019alop\u00e9cie areata avec des antihistaminiques : co\u00efncidence int\u00e9ressante ou nouvelle voie de recherche?<\/p>\n

Dr Jeff Donovan<\/p>\n

Il est difficile de mener des \u00e9tudes sur l\u2019alop\u00e9cie areata. L\u2019une des raisons vient du fait que la repousse des cheveux peut se produire spontan\u00e9ment, m\u00eame si aucun traitement n\u2019est administr\u00e9. Pour cette raison, il est important que tout nouveau m\u00e9dicament qui promet un b\u00e9n\u00e9fice dans le traitement de l\u2019alop\u00e9cie areata soit tr\u00e8s soigneusement \u00e9tudi\u00e9.<\/p>\n

Plusieurs \u00e9tudes ont sugg\u00e9r\u00e9 que les m\u00e9dicaments antihistaminiques contre les allergies pourraient \u00eatre utiles pour traiter l\u2019alop\u00e9cie areata. Toutefois, ces \u00e9tudes \u00e9taient de faibles envergures et nous ne savons toujours pas si ce traitement pourrait \u00eatre utile.<\/p>\n

Par exemple, des chercheurs japonais ont r\u00e9cemment rapport\u00e9 qu’une femme de 19 ans souffrant d\u2019alop\u00e9cie areata \u00e0 l\u2019arri\u00e8re du cuir chevelu (appel\u00e9e pelade ophiasique, un type d\u2019alop\u00e9cie areata) a vu son \u00e9tat s\u2019am\u00e9liorer apr\u00e8s un traitement \u00e0 la fexof\u00e9nadine (commercialis\u00e9e sous les noms Allegra, Telfast, Fastofen, Tilfur, Vif, Telfex, Allerfexo). La jeune femme a d\u2019abord \u00e9t\u00e9 trait\u00e9e avec des st\u00e9ro\u00efdes topiques puissants, mais n\u2019a pas vu d\u2019am\u00e9lioration sur une p\u00e9riode de quatre mois. Apr\u00e8s avoir ajout\u00e9 la fexof\u00e9nadine au traitement, une am\u00e9lioration a \u00e9t\u00e9 constat\u00e9e dans les 3 mois.<\/p>\n

S\u2019agit-il d\u2019une co\u00efncidence ou d\u2019un effet r\u00e9el?<\/strong>
\nLa r\u00e9ponse est : nous ne savons pas.
\nUne pr\u00e9c\u00e9dente \u00e9tude de plus grande envergure portant sur 121 personnes atteintes d\u2019alop\u00e9cie areata avanc\u00e9e a sugg\u00e9r\u00e9 que la fexof\u00e9nadine pourrait aider les personnes atteintes d\u2019alop\u00e9cie qui recevaient un traitement par immunoth\u00e9rapie (soit le DPCP ou l’ester dibutylique d’acide squarique). Mais l\u2019am\u00e9lioration n\u2019a \u00e9t\u00e9 constat\u00e9e que chez les personnes qui avaient des tendances allergiques, c’est-\u00e0-dire celles qui souffraient d\u2019ecz\u00e9ma atopique, d\u2019asthme ou de rhume des foins. Une poign\u00e9e d\u2019autres \u00e9tudes ont sugg\u00e9r\u00e9 que d\u2019autres types d\u2019antihistaminiques pouvaient \u00eatre b\u00e9n\u00e9fiques pour l\u2019alop\u00e9cie areata.
\nIl s\u2019agit d\u2019un domaine int\u00e9ressant pour lequel des recherches plus pouss\u00e9es seraient b\u00e9n\u00e9fiques.<\/p>\n

R\u00e9f\u00e9rence<\/strong>
\nNonomura Y et al. Case of intractable ophiasis type alopecia areata presumably improved by fexofenadine. The Journal of Dermatology 2012 ; 39 : 1-2.
\nInui S. Fexofenadine hydrochloride enhances the efficancy of contact immunotherapy for extensive alopecia areata: Retrospective analysis of 121 cases. Journal of Dermatology 2009 ; 36:323-327.<\/p>\n","protected":false},"excerpt":{"rendered":"

Publi\u00e9: ao\u00fbt, 2012 Traitement de l\u2019alop\u00e9cie areata avec des antihistaminiques : co\u00efncidence int\u00e9ressante ou nouvelle voie de recherche? Dr Jeff Donovan Il […]<\/p>\n","protected":false},"author":1,"featured_media":16460,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[355],"tags":[],"class_list":["post-16062","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-recherche"],"yoast_head":"\nTraitement de l\u2019alop\u00e9cie areata par les antihistaminiques - Fondation Canadienne de l\u2019Alop\u00e9cie Areata<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.canaaf.org\/fr\/traitement-de-lalopecie-areata-par-les-antihistaminiques\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Traitement de l\u2019alop\u00e9cie areata par les antihistaminiques - Fondation Canadienne de l\u2019Alop\u00e9cie Areata\" \/>\n<meta property=\"og:description\" content=\"Publi\u00e9: ao\u00fbt, 2012 Traitement de l\u2019alop\u00e9cie areata avec des antihistaminiques : co\u00efncidence int\u00e9ressante ou nouvelle voie de recherche? 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